Is there not a purpose?
'As a race we feel empty. This is because our spirituality has been wiped out and we don't know how to express ourselves. As a result we're encouraged to fill that gap with alcohol, drugs, sex or money. People out there are screaming for the truth.'
Sinead O'Connor

'There remains in the soul (if I dare use that word) a persistent and unconscious anxiety that something is missing...some ingredient that makes life worth living.'
Prince Charles

'Countries like ours are full of people who have all the material comforts they desire, together with non-material blessings like a happy family, and yet lead lives of quiet and, at times, noisy desperation, understanding nothing but the fact there is a hole inside them, and that however much food or drink they pour into it, however many motor cars and television sets they stuff it with, however many children and friends they parade around the edges of it... IT ACHES.'
Bernard Levin (The Times)

If, there is a Creator and we are here by design, then we are missing something, a relationship with our Maker. It also means that there is an ultimate purpose to life.
As Augustine once put it "You have made us for yourself, O Lord, and our hearts are restless till they find their rest in you".
The Bible teaches that we were made by God to know him but have lost this relationship. There is something missing in all our lives until we find him again.
If there is not a Creator, we also have to face the big question of what happens when we die...